Methylene Blue

So - over the years Nathan has had all sorts of medications. He is currently getting the weirdest one - methylene blue. He is getting the chemo ifosfamide and it can can neuro-toxicity as described here: Ifosfamide is an alkylating agent with well-demonstrated efficacy against a large number of malignant diseases. With cyclophosphamide it shares a toxicity profile characterized by myelosuppression and urotoxicity, but ifosfamide has additionally disclosed adverse neurological effects. Ifosfamide-related central nervous system toxicity is characterized by metabolic encephalopathy of varying severity. Symptoms have been reported in 5-30% of all patients treated with ifosfamide. Copyright © 2003 S. Karger AG, Basel

They have found that treating with methylene blue can prevent the toxicity.

So - you can see from the picture that it is very dark blue. It is the color of the bottle. It was bizarre to see it pushed through Nathan's IV. He is now proudly peeing blue. It isn't just bluish - it is bright blue. His other bodily fluids are also blue. He has had each of us take a look at his blue pee - I am glad he gets a kick out of it at least.